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CARLO ERBA Reagents offers you an excellent substitute to THF or 2-MeTHF: MTHP (4-Methyltetrahydropyran).

This hydrophobic cyclic ether is suitable for many reactions (Grignard reactions, LAH reduction, cross coupling, etc).

What are the main benefits of this solvent?
  • High hydrophobicity

Easily separable from water: recyclable, no extraction solvent needed...

It simplifies your manufacturing process.

  • High solvency power

Similar solubility to THF: it can therefore dissolve polar compounds

  • High boiling point (105°C)
  • Oxidation resistance

MTHP is stable towards auto-oxidation. It also means that it is easier to store and recycle.

  • High stability in acidic and basic medium

MTHP is a robust molecule and can be used under severe conditions in reactions such as esterification and acetalization with an acidic catalyst, cationic polymerization using acid chlorides, reduction with LAH, […]

  • Reactions examples :
    • Better yields
    • Shorter reaction times
    • fewer steps

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    ​​​​​​MTHP

    CARLO ERBA Reagents offers this solvent in “RE - Pure for synthesis” quality, stabilized with BHT and suitable for all organic synthesis processes from 500 ml to 2.5l and also in ERBAdry® quality ( the range of anhydrous solvents, with its innovative packaging)

    More information on our ERBAdry® range